Primary structure measurements of biomolecules

Biomolecule quantification and characterisation

The development of new products in life sciences and health relies on purity measurements, quantification and characterisation of biomolecules. This can be accurately achieved through techniques like high resolution liquid chromatography (hr)LC and mass spectrometry (MS). Materials can also be assessed for structural impurities, for instance, peptidic materials can be assessed for truncations, deletions and additions.

Measurements are reported by mass spectrometry relative and fractional abundance. The data can be used on a stand-alone basis or in a complementary way by linking to other techniques used for purity analysis and establishing an unbroken chain of traceability. We also have expertise and a traceable methodology for made peptides.

Standard measurements include:

• Purity
• Separation, identification and characterisation of small and large molecules
• Peptide mass fingerprinting (PMF)
• Tandem mass spectrometry
• Chemical or biological matrices
• Lipidomics
• High throughput screening and confirmation
• Traceable measurements

Quantitative measurements can be taken from as little as 2.5 μg/mL per sample.

Don’t see what you are looking for? Our diverse skill set enables us to provide bespoke solutions. Please contact us to discuss your requirements.

Contact us