Cryogenic-electron microscopy (CryoEM)

High resolution biological imaging at near atomic levels

NPL has expanded its comprehensive biological imaging capabilities to include Cryogenic-electron Microscopy (CryoEM). This powerful technique allows our research teams to see the structure of biomolecules with near atomic precision. CryoEM techniques not only enable an increased understanding of the detailed structural biology of molecules and pathogens but allows the design and development of drugs that have an increased chance of successfully interacting with their intended target. This makes CryoEM a vital imaging technique in understanding and treating diseases and developing the therapeutics to combat them.

As the UK’s National Metrology Institute, we can utilise our team’s expertise and background in metrology across all aspects of the CryoEM imaging process – from sample preparation to image acquisition and data analysis – to ensure that accurate data is captured, analysed and reported.

To learn more, contact our expert team to find out how we can help.

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How can we help

The combination of metrology expertise and experience with a wide range of imaging platforms, means that we are ideally suited to assist organisations that are new to using CryoEM as a technique. Our microscopy team is able to offer expertise and guidance through each step of the sample preparation and analysis process.

We have an extensive range of complementary biological imaging capabilities and expertise to support life science research available under one roof, so the team is ideally positioned to support drug discovery and disease progression research programmes.